Is this a relapse or a pseudoexacerbation?

Photo of a paint brushesRecognizing the difference between a true relapse and a pseudoexacerbation can be confusing. To follow are the criteria for a relapse versus a short-term flare-up of symptoms (usually subsiding within 24 hours). You should call your neurologist or healthcare team about the possibility of a relapse when you are experiencing new or worsened symptoms and the following criteria are met:

  • The new or recurring symptom(s) has been present for at least 24 hours
  • It’s been less than 24 hours, but your symptoms are severe and could affect your health or safety
  • You do not have a fever or any other signs of infection, e.g., a urinary tract infection (please note: if you do have signs of an infection, consult your physician immediately for treatment of the infection)
  • Your body is not overheated, which may result from the temperature around you, exercise, etc.
  • You didn’t overexert yourself today and do too much
  • You aren’t having an unusually stressful day

It’s important to note that you should not dismiss symptoms simply because you feel that you may have been under significant stress.


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