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Promising Testing Method For Spinal Cord Injuries, Multiple Sclerosis
A medical test previously developed to measure a toxin found in tobacco smokers has been adapted to measure the same toxin in people suffering from spinal cord injuries and multiple sclerosis, offering a potential tool to reduce symptoms...
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Speeding Up Multiple Sclerosis Research Using New Imaging Technique
Researchers at the University of British Columbia have developed a new magnetic resonance imaging (MRI) technique that detects the telltale signs of multiple sclerosis in finer detail than ever before - providing a more powerful tool for evaluating new treatments. The technique analyzes the frequency of electro-magnetic waves collected by an MRI scanner, instead of the size of those waves...
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Switching To Gilenya® (Fingolimod) From Standard Interferon Offers Sustained Freedom From Disease Activity For People With Relapsing Remitting MS
Two new analyses from the pivotal Phase III TRANSFORMS study presented at the European Neurological Society (ENS) have shown early and sustained improvements in disease activity in patients who were switched from an interferon to Gilenya® (fingolimod). Improvements were seen within 12 months of the switch and were sustained up to 4...
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Personalised Therapy For Multiple Sclerosis Is Key Factor In Treatment Success
"Although the upcoming approval of new drugs against multiple sclerosis will offer a number of additional treatment options, it is important that we keep one thing in mind: The only way we can get this disease well under control is if we manage to provide personalised therapy tailored to the individual and to predict the effects and side-effects of a...
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Phase 1 Multiple Sclerosis Trial Safely Resets Patients' Immune Systems And Reduces Attack On Myelin Protein
A phase 1 clinical trial for the first treatment to reset the immune system of multiple sclerosis (MS) patients showed the therapy was safe and dramatically reduced patients' immune systems' reactivity to myelin by 50 to 75 percent, according to new Northwestern Medicine research...
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MS Treatment That Resets Immune System Shows Promise In Safety Trial
A new treatment for multiple sclerosis (MS) that resets the patient's immune system was found to be safe and well tolerated in a small trial published in Science Translational Medicine this week. And, although not designed to test the effectiveness of the therapy, the trial also showed promising results in this area...
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A New Approach To Multiple Sclerosis
In his article, "Pathoetiology of multiple sclerosis: are we barking up the wrong tree?", Peter K...
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Multiple Sclerosis, Parkinson's Disease And Muscular Degeneration Could Be Impacted By Stem Cell Study
Scientists have taken a vital step forward in understanding how cells from skin tissue can be reprogrammed to become stem cells. New research could pave the way to generate these stem cells efficiently to better understand and develop treatments for diseases such as multiple sclerosis, Parkinson's disease and muscular degeneration...
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In Multiple Sclerosis-like Disease, Enhanced White Blood Cells Heal Mice
Genetically engineered immune cells seem to promote healing in mice infected with a neurological disease similar to multiple sclerosis (MS), cleaning up lesions and allowing the mice to regain use of their legs and tails...
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Immune Cell Activation In Multiple Sclerosis
Biological processes are generally based on events at the molecular and cellular level. To understand what happens in the course of infections, diseases or normal bodily functions, scientists would need to examine individual cells and their activity directly in the tissue. The development of new microscopes and fluorescent dyes in recent years has brought this scientific dream tantalisingly close...
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Biogen Idec Submits Application To FDA For Approval Of Plegridy™ (Peginterferon Beta-1a) In Multiple Sclerosis
EMA Submission Planned in the Coming Weeks Biogen Idec (NASDAQ: BIIB) has announced it has submitted a Biologics License Application (BLA) to the U.S. Food and Drug Administration (FDA) for approval of PLEGRIDY™ (peginterferon beta-1a), the company's pegylated subcutaneous injectable candidate for relapsing forms of multiple sclerosis (RMS)...
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Researchers Able To Prevent And Cure Type 1 Diabetes In Animal Models
Melbourne researchers have identified an immune protein that has the potential to stop or reverse the development of type 1 diabetes in its early stages, before insulin-producing cells have been destroyed...
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New Approach To Improving Treatment For Multiple Sclerosis And Other Conditions
Working with lab mice models of multiple sclerosis (MS), UC Davis scientists have detected a novel molecular target for the design of drugs that could be safer and more effective than current FDA-approved medications against MS...
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Cells Aid In Scar Formation After Injury To Central Nervous System
By monitoring the behavior of a class of cells in the brains of living mice, neuroscientists at Johns Hopkins discovered that these cells remain highly dynamic in the adult brain, where they transform into cells that insulate nerve fibers and help form scars that aid in tissue repair...
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Multiple Sclerosis More Common In Black Women Than White
Multiple sclerosis (MS) is more common in black women than in white women, according a new study. The research was conducted by Kaiser Permanente and was published in the journal Neurology. The results contradict the widely believed notion that black people are less vulnerable to the disease. The electronic health records of over 3...
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Peli1 Identified As Pivotal Actor In Animal Model Of Multiple Sclerosis
Scientists have identified an influential link in a chain of events that leads to autoimmune inflammation of the central nervous system in a mouse model of multiple sclerosis (MS). An international team of researchers led by scientists in The University of Texas MD Anderson Cancer Center Department of Immunology reported their results in an advance online publication in Nature Medicine...
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How Turning Down Synthesis Of A Protein Improves Nerve, Muscle Function In Common Neuropathy
A potential new treatment strategy for patients with Charcot-Marie-Tooth disease is on the horizon, thanks to research by neuroscientists now at the University at Buffalo's Hunter James Kelly Research Institute and their colleagues in Italy and England...
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Infection With Roundworm Quells Obesity And Related Metabolic Disorders
Researchers at the University of Maryland School of Medicine, Baltimore, have shown in a mouse model that infection with nematodes (also known as roundworms) can not only combat obesity but ameliorate related metabolic disorders. Their research is published ahead of print online in the journal Infection and Immunity...
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Atrophy In Key Region Of Brain Associated With Multiple Sclerosis
Magnetic resonance imaging (MRI) measurements of atrophy in an important area of the brain are an accurate predictor of multiple sclerosis (MS), according to a new study published online in the journal Radiology. According to the researchers, these atrophy measurements offer an improvement over current methods for evaluating patients at risk for MS...
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Data Gathered Reveals Extent Of Alternative Medicine Use By MS Patients
A major Nordic research project involving researchers from the University of Copenhagen has, for the first time ever, mapped the use of alternative treatment among multiple sclerosis patients - knowledge which is important for patients with chronic disease and the way in which society meets them...
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New Technique Holds Promise For The Treatment Of Multiple Sclerosis And Cerebral Palsy
Researchers at Case Western Reserve School of Medicine have discovered a technique that directly converts skin cells to the type of brain cells destroyed in patients with multiple sclerosis, cerebral palsy and other so-called myelin disorders. This discovery appears in the journal Nature Biotechnology...
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Incurable Neurological Disorder HDLS Often Incorrectly Diagnosed As Alzheimer's Disease, MS Or Parkinson's Disease
The very serious hereditary disease HDLS was discovered in 1984 in Sweden. Many HDLS patients are still incorrectly diagnosed with Alzheimer's disease, MS or Parkinson's disease, but researchers at the Sahlgrenska Academy, University of Gothenburg, Sweden, have now developed a more certain diagnosis method - and are seeking to find a treatment for the "unknown" neurological disorder...
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Minocycline Show Benefits In Children With Inherited Cause Of Intellectual Disability And Autism
The antibiotic drug minocycline yields "modest" but meaningful improvements in functioning and mood for children with fragile X syndrome (FXS), reports a study in the April Journal of Developmental & Behavioral Pediatrics, the official journal of the Society for Developmental and Behavioral Pediatrics. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health...
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Immune System Development Influenced By Birth Month
Newborn babies' immune systems and vitamin D levels vary, depending on which month of the year they are born. These findings come from scientists at Queen Mary, University of London and the University of Oxford and were published in the journal JAMA Neurology...
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