Frequently Asked Questions
- What is multiple sclerosis?
- What causes MS?
- Is MS fatal? Can MS be treated?
- What Type of doctor specializes in MS? How is MS Diagnosed?
- Who gets MS? How many people have MS?
- Does MS or its treatments pose any risks to becoming pregnant?
- Can I inherit MS?
Multiple sclerosis, also referred to as “MS,” is a neurological disorder affecting the nerves of the brain and spinal cord. MS is thought to be an “autoimmune” disease, which means that a person’s own immune system is attacking his or her body. This attack damages the protective covering to the nerves (myelin) and eventually the nerves (axons) as well.
MS is most often diagnosed in young adults, and symptoms can range from visual changes, numbness, and vertigo, to bladder and bowel problems, weakness, and spasticity (muscle tightness), among other symptoms. Individuals may also experience emotional difficulties, such as depression, or cognitive issues, such as forgetfulness. For most people with early MS, symptoms tend to flare up (“relapse”) and subside (“remit”) for long periods of time.
For more information, please visit our MS Overview section of MSAA’s website.
While we know that MS is not contagious, an exact cause of this disease has yet to be determined. Most researchers believe that more than one factor is involved in the development of MS. One popular theory involves a slow-acting virus, such as Epstein-Barr virus (EBV) or measles, which could remain dormant (inactive) for many years before contributing to the development of MS in genetically susceptible people.
MS is not hereditary, but having more than one family member diagnosed with MS is not uncommon. Numerous studies have shown that this increased risk among family members is a result of sharing DNA, and not a result of sharing the same environment. Therefore, genes play a role to some degree.
Additionally, researchers are now looking at a vitamin D deficiency (vitamin D may be derived from both sunlight and diet), along with the types and amounts of fat intake in one’s diet, as possible contributing factors to MS. Cigarette smoking is another factor that can be involved in the development of MS. It not only increases one’s risk of developing MS, but also increases the rate of progression of one’s MS.
For more information, please visit our Possible Causes of MS section of MSAA’s website.
Only a small percentage of patients experience a rapidly progressive type of MS, which may cause more significant health issues early in the disease. Some individuals, particularly those who are significantly inactive, may experience the typical complications of a prolonged chronic illness (such as infection or pneumonia). Additionally, a recent study has shown that for individuals with relapsing forms of MS, those who begin treatment early with a disease-modifying therapy and stay on the therapy, may live longer than those who are not on treatment.
With various adjustments made along the way, most individuals with MS may look forward to a full and productive life. As for anyone, other health factors play a role in determining an individual’s quality of life as well as life expectancy. Examples of such health factors include diet, exercise, whether or not someone smokes, alcohol consumption, and family history of disease.
While no cure for MS has been found, 13 FDA-approved drugs are now available for the long-term treatment of MS. These have been shown to reduce the number and severity of MS flare-ups, along with possibly slowing disease progression. Many more experimental MS therapies are being studied in clinical trials, and these may lead to more treatment options — and possibly a cure — for MS.
Since MS is a neurological condition, it is usually diagnosed and treated by a neurologist. Other professionals specializing in neurology in conjunction with another area of medicine – such as radiology (neuroradiologist), ophthalmology (neurophthalmologist), and psychology (neuropsychologist) — may also assist with one’s diagnosis and ongoing treatment plan.
Because the symptoms of early MS can come and go, and because a single test is not yet available to determine if one has MS, getting a diagnosis is often difficult. Several appointments and tests (to exclude other conditions) may be necessary.
Tools used to help diagnose and evaluate MS include:
- magnetic resonance imaging (MRI)
- magnetic resonance spectroscopy (MRS)
- lumbar puncture (spinal tap)
- evoked potentials (EP) tests
- Expanded Disability Status Scale (EDSS)
- Functional System (FS) scale
- MS Functional Composite (MSFC) scale
For more information, please see the “Diagnosing MS and Evaluating Disease Activity” section of our website.
Most people with MS experience their first symptoms and are diagnosed between the ages of 15 and 50. Previously, MS in younger children was extremely rare. Referred to as “Pediatric MS,” the diagnosis of MS at a young age is on the rise. Researchers do not know if this is an indication of people developing MS at an earlier age, or if this is a result of greater disease awareness and more sensitive diagnostic procedures.
Women are two to three times more likely to develop MS versus men. Caucasians, especially those of European or Scandinavian ancestry, are at a much greater risk of MS than those of African heritage.
Individuals growing up in regions closer to the equator have a lower incidence of MS. The rate of MS increases as distance from the equator increases. This environmental factor may relate to diet, exposure to sunlight, and/or other lifestyle traits.
Estimates of MS populations vary, and specific numbers are difficult to confirm through healthcare organizations. Many groups estimate that 400,000 individuals in the United States have MS, although this number could be much higher. Additionally, estimates range from one to two-and-a-half million for people living with MS throughout the world.
The North American Research Committee on Multiple Sclerosis (NARCOMS) has an MS registry with an active database of more than 35,000 individuals with MS. If you are interested in learning more or becoming a part of this registry, please visit narcoms.org.
For more information on Who Gets MS, please refer to this section under the “MS Overview” section of MSAA’s website.
Many of those diagnosed with MS are young women with plans of having children at some point in their future. The good news is that MS does not affect fertility, and pregnancies progress “normally” (that is, having the same benefits and risks as someone without MS).
For most women with MS, MS symptoms often stabilize or improve during pregnancy. Unfortunately, 20-to-40 percent of women have a relapse following delivery, so new mothers will need to plan for more rest and assistance during the first few months. Disease progression and long-term risk of additional relapses are not affected by pregnancy.
Some of the medications taken for MS can increase the risk of miscarriage and are transmitted in breast milk. Women considering pregnancy should discuss their medications with their neurologist in advance. Some medications may need to be discontinued for a few months before attempting to become pregnant.
Having a child is an important decision for any person or couple. With MS, parents need to consider that fatigue and other symptoms may affect the amount of activity the mother may be able to perform with the child or children in their younger years. Assistance from others – such as family and friends – may be needed at certain times. Before making the commitment, individuals and couples may want to discuss these pregnancy-related issues with their healthcare team.
Many people ask if MS may be inherited. While MS in not hereditary, individuals may be “genetically susceptible,” increasing their risk of MS. This risk is slight, with only a three-to-four percent chance of a child (with a parent who has MS) being diagnosed with MS sometime in his or her future.
Researchers believe that genetics are only one piece to the puzzle, and other factors (such as common viruses, environment, diet, etc.) are also necessary to develop MS. Additionally, MS research is making great strides toward identifying causes and fine-tuning effective treatments.
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