Aubagio® is an immunomodulatory disease-modifying therapy that helps support the immune system.
7mg or 14mg, daily
Relapsing forms of multiple sclerosis in adults, including clinically isolated syndrome, relapsing-remitting MS, and active secondary-progressive MS
- 7 mg showed a 22% reduction in relapses compared with placebo.
- 14 mg showed a 36% reduction in relapses compared with placebo.
- 7 mg showed a 33% reduction in total lesion volume.
- 14 mg showed 67% reduction in total lesion volume.
- Aubagio was shown to be effective vs. placebo in the three key measures – relapses, brain lesions, and disability progression.
Common Potential Side Effects
Hair thinning, diarrhea, headache.
For assistance finding additional resources that might help cover the costs of your prescription, contact MSAA.
HOW Aubagio® WORKS
Aubagio®, a tablet taken once per day by mouth, is an immunomodulator. MS relapses are triggered by overactive immune cells. Aubagio® blocks an enzyme necessary for the growth of these overactive immune cells. By blocking this enzyme, fewer of these damaging cells are found in the brain and spine.
Aubagio® was FDA-approved in 2012. It is approved to treat relapsing forms of MS, including clinically isolated syndrome, relapsing-remitting disease, and active secondary-progressive disease, in adults.
Potential Side Effects
Headache, elevations in liver enzymes, hair thinning, diarrhea, nausea, neutropenia (a condition in which there is a reduced number of certain white blood cells), and paresthesia (tingling, burning, or numbing sensation). More severe adverse events include the risk of severe liver injury, hypertension and risk of fetal harm.
OTHER KEY INFORMATION
Labs completed prior to starting Aubagio® include:
- Cell count
- Liver function tests
- Tuberculosis test
Labs after starting Aubagio® include:
- Monthly liver function tests for the first six months
- Following these initial tests, your clinician will likely order cell count and liver function tests every six months.
Patient advocates talk about
their treatment experience
Kristie Salerno Kent“I have had situations where treatments aren’t approved at first. My doctors, nurses, they actually go to bat for me and made it happen.”
Azure Antoinette"I will be undergoing my first disease-modifying therapy to help treat multiple sclerosis in my body and while I’m very nervous, I am equally as excited and looking forward to the positive effects of how I will feel physically, and mentally, and emotionally."
Damian Washington“Nobody’s going to be looking out for your best interests better than you.”
Cathy Chester“I think it’s really important to talk about how to age with this illness.”
Lauren Hutton-Work“Just because you have this disease does not mean that your work life should be awkward or uncomfortable.”
Chernise Joseph“My first neurologist was a frontline neurologist, he wasn’t an MS specialist.”
Julian Gamboa“If you’re newly diagnosed with multiple sclerosis remember it’s always okay to get a second opinion.”
Lauren and Sam Alcorn“Our future is uncertain and we have to enjoy each other and love each other in the present.”
Shawn Feliciano“I want to know what medications might work best for someone who’s Hispanic.”
Darlene Feigen“The sooner you get on a therapy the better it is in the long run.”
Birgit Bauer“At the end of the appointment you should have an answer to the most important questions.”
Ellen Tutton“I looked up all the different disease-modifying therapies and compared them to my lifestyle.”
Victoria Marie Reese“I’m trying to show my daughter that taking care of yourself is cool.”