Aubagio® is an immunomodulatory disease-modifying therapy that helps support the immune system.
7mg or 14mg, daily
Relapsing forms of multiple sclerosis in adults, including clinically isolated syndrome, relapsing-remitting MS, and active secondary-progressive MS
- 7 mg showed a 22% reduction in relapses compared with placebo.
- 14 mg showed a 36% reduction in relapses compared with placebo.
- 7 mg showed a 33% reduction in total lesion volume.
- 14 mg showed 67% reduction in total lesion volume.
- Aubagio was shown to be effective vs. placebo in two of the three key measures—relapses and brain lesions—but not disability progression.
Common Potential Side Effects
Hair thinning, diarrhea, headache.
For assistance finding additional resources that might help cover the costs of your prescription, contact MSAA.
HOW Aubagio® WORKS
Aubagio®, a tablet taken once per day by mouth, is an immunomodulator. MS relapses are triggered by overactive immune cells. Aubagio® blocks an enzyme necessary for the growth of these overactive immune cells. By blocking this enzyme, there are less of these cells to damage in the brain and spine.
Aubagio® was FDA-approved in 2012. It is approved to treat relapsing forms of MS, including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.
Potential Side Effects
Headache, elevations in liver enzymes, hair thinning, diarrhea, nausea, neutropenia (a condition that reduces the number of certain white blood cells), and paresthesia (tingling, burning, or numbing sensation). More severe adverse events include the risk of severe liver injury, hypertension and risk of fetal harm.
OTHER KEY INFORMATION
Labs completed prior to starting Aubagio® include:
- Cell count
- Liver function tests
- Tuberculosis test
Labs after starting Aubagio® include:
- Monthly liver function tests for the first six months
- Your clinician will likely order cell count and liver function tests every six months after that
Patient advocates talk about
their treatment experience
Kristie Salerno Kent“I have had situation where treatments aren’t approved at first. My doctors, nurses, they go actually go to bat for me and made it happen.”
Azure Antoinette“I wish would have had access or agency to get seen sooner and to treat this sooner.”
Damian Washington“Nobody’s going to be looking out for your best interests better than you.”
Cathy Chester“I think it’s really important to talk about how to age with this illness.”
Lauren Hutton-Work“Just because you have this disease does not mean that your work life should be awkward or uncomfortable.”
Chernise Joseph“My first neurologist was a frontline neurologist, he wasn’t an MS specialist.”
Julian Gamboa“If you’re newly diagnosed with multiple sclerosis remember it’s always okay to get a second opinion.”
Sam and Lauren Alcorn“Our future is uncertain and we have to enjoy each other and love each other in the present.”
Shawn Feliciano“I want to know what medications might work best for someone who’s Hispanic.”
Darlene Feigen“The sooner you get on a therapy the better it is in the long run.”
Birgit Bauer“At the end of the appointment you should have an answer to the most important questions.”
Ellen Tutton“I looked up all the different disease modifying therapies and compared them to my lifestyle.”
Victoria Marie Reese“I’m trying to show my daughter that taking care of yourself is cool.”