Spring 2009 Research Update

In January 2009, Merck Serono (Geneva Switzerland) announced results of their Phase III CLARITY trial. According to the release, cladribine tablets met the two-year endpoint of reducing the relapse rate in patients with relapsing-remitting MS (RRMS). More than 1300 patients with RRMS participated in the CLARITY study, which was a 96- week, randomized, double-blind, placebo-controlled, international trial.

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Results Announced from the Phase II Study of Dirucotide (MBP8298) in RRMS Patients

Dirucotide, previously known as MBP8298, has been in clinical trials primarily for the treatment of secondary-progressive multiple sclerosis (SPMS), but also for relapsing-remitting multiple sclerosis (RRMS). On January 30, 2009, dirucotide’s developer (BioMS Medical Corp.), announced the results of MINDSET-01, an exploratory phase II clinical trial designed to evaluate the effectiveness and safety of dirucotide in patients with RRMS.

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Fall 2008 Research Update

More than 5,000 medical professionals attended this year’s first World Congress on Treatment and Research in Multiple Sclerosis, held in Montreal, Canada this past September. MSAA’s Chief Medical Officer Jack Burks, MD, not only attended the meeting, but also reviewed approximately 1,000 poster presentations – specifically about the latest in MS news and research.

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Changes to Tysabri’s Labeling

Two changes have recently been made to the labeling and prescribing information for Tysabri® (natalizumab). Manufactured and marketed by Biogen Idec and Elan, Tysabri is approved by the United States Food and Drug Administration (FDA) for the treatment of multiple sclerosis (MS) as well as Crohn’s disease.

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Summer Research Update 2008

Numerous trials are currently being conducted to determine the safety and effectiveness of medications for the treatment of multiple sclerosis (MS). Trials include FDA-approved drugs, experimental drugs (such as oral medications, monoclonal antibodies, and other treatments), as well as various combinations of drugs and doses.

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